Also in action was Kelechi Iheanacho who saw action for 90 minutes.
It was Moses’ first goal in 16 appearances in all competitions for Spartak Moscow so far in this campaign.
Spartak took the lead in the 51st minute thanks to Moses who started the move, lifting the ball to Ruslan Litvinov before barrelling into the area and was left unmarked to glance in Mikhail Ignatov’s fine cross.
But Leicester were behind for just seven minutes as Ghana’s Daniel Amartey headed in after Ayoze Perez flicked on Ryan Bertrand’s corner.
Jamie Vardy was then summoned from the bench with 20 minutes left and, five minutes later, blew the golden chance when Moses fouled Ademola Lookman in the box.
It would have been an instant impact but the Vardy’s penalty was poor and Selikhov pushed it away.
The result means Leicester are now in third position on five points while Spartak are bottom on four points with two games left to play.
Napoli top the group and are on seven points with Legia Warsaw in second spot on six points.
Midtjylland occupy third position on five points just four points separate them from leaders Sporting Brats.
And in the Europa Conference League, Cyriel Dessers scored the winning goal as Feyenoord defeated Taiwo Awoniyi’s Union Berlin 2-1 in Group E.
It was Dessers’ first goal after four appearances in the competition. He now has five goals in 16 appearances in all competitions.
While Dessers was brought on in the 64th minute, Awoniyi came on in the 59th minute.
With score at 1-1, Dessers netted what proved to be the winner in the 72nd minute for the Dutch giants.
Cyriel Dessers celebrating his winning goal against Union Berlin
Union Berlin had two players sent off with Christopher Trimmel (scorer for Union Berlin) and Cedric Teuchert given their matching orders.
Following the win, Feyenoord extend their lead at top as they are now on 10 points and are four points above secons-placed Peter Olayinka’s Slavia Prague.
Union Berlin are in fourth with three points after four games played.
By James Agberebi
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